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Revolutionizing Personalized Medicine: A New All-in-One Sensor System for Monitoring Stem Cell Cultures
According to recent research published in Science Advances, a groundbreaking all-in-one sensor system capable of continuously monitoring stem cell cultures has been developed. This innovative sensor system aims to facilitate the large-scale production of high-quality stem cells at a low cost, pushing the boundaries of personalized medicine. The development of this sensor system is a crucial stride towards addressing the increasing demand for scalable and efficient production of stem cells for medical applications.
The CellXpress.ai Automated Cell Culture System is an AI-driven cell culture innovation hub that allows for total control over demanding cell culture feeding and passaging schedules. The system significantly reduces hands-on time in the lab, maximizing productivity for growing and scaling multiple stem cell lines, spheroids, or organoids. The system offers actionable imaging, turnkey protocols, and machine learning-assisted solutions to standardize the development process and deliver consistent biologically relevant results at scale.
As discussed on Nature, the new all-in-one sensor system for monitoring stem cell cultures provides real-time monitoring of key parameters such as pH, oxygen levels, and temperature. This system aims to significantly improve the efficiency and accuracy of stem cell culture monitoring.
An article on ScienceDirect discusses the development of an in-line cell density sensor for hollow fiber bioreactors (HFBRs) that allows for non-invasive monitoring of localized cell densities. Hollow fiber bioreactors have been utilized for cell culturing since the 1970s due to their high surface to volume ratio facilitating efficient nutrient exchange and high cell density growth. The proposed sensor offers minimal disruption to the cell culture system while demonstrating impedance-based sensing capabilities.
The Nature journal also discusses the development of a portable CO2 cell culture mini incubator that facilitates long term live cell imaging. It provides and maintains stable environmental conditions and supports cell viability, allowing for parallel experiments in the same environment. The importance of time-lapse imaging in providing valuable insights into dynamic cellular behaviors is also emphasized.
The SpectraMax iD3 and iD5 Multi Mode Microplate Readers are equipped with NFC functionality and a large touchscreen for multi-user usability. They measure absorbance, fluorescence, luminescence, TRF, FP, TR FRET, HTRF, BRET, dual luciferase reporter assays, and western blot detection. The optical system includes a xenon flash lamp and a PMT detector for high sensitivity and a wide dynamic range. The QuickSync feature allows data transfer in Excel compatible format and the temperature control adjusts from ambient up to 66C.
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