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Discover CellRaft Technology to Increase the Growth of Colonies and Organoids : Get Quote, RFQ, Price or Buy

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The CellRaft Air® System is an integrated platform that uses specialized technology to keep cells in an unperturbed state, resulting in enhanced viability of single cells, highly proliferative colonies, and superior clonal outgrowth. This rapidly increases the number of clones available for downstream applications. Hydraulic Moulding Line

Discover CellRaft Technology to Increase the Growth of Colonies and Organoids : Get Quote, RFQ, Price or Buy

Users can use the system to:

Seeding cells on the CellRaft array is as simple as seeding cells on any regular tissue culture dish. Cells settle into the microwells by gravity after the dilute cell suspension is dispensed into the central reservoir. The CellRaft Arrays are intended to produce many single cells while benefiting from shared media in a flask-like environment to promote viability and monoclonal outgrowth.

Brightfield and fluorescence scanning can offer single-cell resolution imaging in as short as seven minutes. Because the CellRaft arrays are keyed, they can be scanned throughout the days or weeks required to identify samples of interest without monopolizing the instrument with a single experiment.

CellRaft CytometryTM enables image-based validation of single cells to ensure monoclonality and analyze parameters ranging from morphology to gene expression. Users can easily define the target cells’ or colonies’ properties and map them for software-guided CellRaft selection for downstream isolation.

After detection, the CellRafts are delicately dislodged from the CellRaft Array with a release needle and recovered from the array with a magnetic wand for downstream processing. The completely automated CellRaft AIR System separates validated, intact clones for proliferation without dissociation or fluidics in a gentle, dissociation-free manner.

The CellRaft Array’s flask-like culture conditions, along with the automated and gentle isolation of specified cells, colonies, or organoids of interest, result in a higher post-isolation outgrowth percentage than can be achieved with limiting dilution or typical cell sorters and dispensers.

Clonal outgrowth efficiency of CHO-K1 cells in n = 3 96-well plates using limiting dilution and CellRaft AIR with 100s and 200s array formats. Image Credit: Cell Microsystems

iPSCs grown on a CellRaft Array. The CellRaft is isolated on Day 6 into a 96-well plate where the iPSCs continue growing off the CellRaft. Image Credit: Cell Microsystems

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Discover CellRaft Technology to Increase the Growth of Colonies and Organoids : Get Quote, RFQ, Price or Buy

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