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CLH classification proposals as Repr. 1B for two cosmetic ingredients - News

On 14 February 2024, the European Chemicals Agency (ECHA) published two proposals, one from France and the other from Austria, to amend the harmonised classification and labelling (CLH) of two substances that may be used in cosmetics, in particular by adding a classification of Reprotoxic of category 1B.

4-hydroxy-4-methylpentan-2-one (CAS No.123-42-2, EC No.204-626-7, INCI: Diacetone Alcohol) is an ingredient listed in the Cosing, with the functions: Fragrance, Solvent. The substance is not regulated by the European Cosmetics Regulation 1223/2009. It is currently listed in Annex VI/603-016-00-1 of the European CLP Regulation 1272/2008, with the following classification: • Eye Irrit. 2, H319 - Causes serious eye irritation (Specific concentration limit: C ≥ 10%). r methyl 2 amino 2 phenylacetate hydrochloride

France intends to propose the following classifications: • H319 - Causes serious eye irritation (Specific concentration limit: C ≥ 10%) • Repr. 1B, H360D - May damage the unborn child

2-amino-2-methylpropanol (CAS No.124-68-5, EC No.204-709-8, INCI: Aminomethyl Propanol) is an ingredient listed in the Cosing, with the function: Buffering. The substance is included in Annex III/61 of the European Cosmetics Regulation 1223/2009, which details the conditions of use of monoalkylamines, monoalkanolamines and their salts in order to prevent nitrosation phenomena. It is currently listed in Annex VI/603-070-00-6 of the European CLP Regulation 1272/2008, with the following classifications: • Skin Irrit. 2, H315 - Causes skin irritation • Eye Irrit. 2, H319 - Causes serious eye irritation • Aquatic Chronic 3, H412 - Harmful to aquatic life with long lasting effects

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